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10 hotels in Saint Charles: Best hotel deals for 2023

Discover the best hotels in Saint Charles, Missouri including Holiday Inn Express & Suites St Charles, an IHG Hotel, Drury Plaza Hotel St. Louis St. Charles, Country Inn & Suites by Radisson, St. Charles, MO, Hampton Inn St. Charles St. Peters, Embassy Suites by Hilton St. Louis St. Charles, Ameristar Casino Resort Spa St. Charles, Best Western Plus The Charles Hotel, Tru by Hilton St. Charles St. Louis, Research Park Inn St. Louis West - Chesterfield, Americas Best Value Inn & Suites St. Louis, St. Charles Inn.